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Research Associate in Computational Image Analysis for Microscopy

University of Sheffield

Sheffield, United Kingdom

Summary:

This post is funded by a BBSRC project grant to investigate the development and function of the zebrafish inner ear from embryo through to the adult. The project aims to use, develop and implement software for the computational analysis of large imaging datasets generated by light-sheet microscopy. You will contribute to the analysis of 4D imaging datasets of the developing zebrafish inner ear, which are being generated in the Whitfield lab. This will involve the use and development of novel tools for automated cell segmentation, tracking and quantitative analysis.

The Department of Electronic and Electrical Engineering is respected internationally for the important contributions it makes in this field. It has the second highest research income in the UK in this subject area. We are a vibrant community of 46 academic staff, including 22 professors, 76 research staff, 34 technical staff, 26 administrative staff and over 800 undergraduate and postgraduate students. The Department is organised into four research groups: Communications and Imaging, Electrical Machines and Drives, Centre for Computational Imaging & Simulation Technologies in Biomedicine (CISTIB) and Semiconductor Materials and Devices. For further information about the Department of Electronic.

The post holder will work within the “Centre for Computational Imaging and Simulation Technologies in Biomedicine (CISTIB) based at the Faculty of Engineering in Sheffield but will also spend regular time with, and liaising with, the Whitfield team. CISTIB focuses on algorithmic and applied research in the areas of computational imaging, and image-based computational physiology modelling and simulation. The Group contributes in different areas of medical image computing and image-based biomechanical and computational physiology modelling, and works in very close cooperation with clinicians from various research centres from the University of Sheffield and the 5 academic hospitals of the Sheffield Teaching Hospital Trust Foundation, the largest NHS Trust of the UK. The Whitfield lab is a member of the Bateson Centre within the Department of Biomedical Science. Our research interests are in the development and function of the vertebrate inner ear, the sensory organ of hearing and balance.

The successful candidate must have been awarded a PhD (or equivalent) in a subject relevant to biomedical image analysis with particular interest or expertise in biological image analysis, microscopy or histopathology, medical image computing, computer vision or machine learning. Preference will be given to applicants with a proven record of accomplishments in image analysis for microscopy. You will present your research findings at scientific meetings, assist in the preparation of manuscript drafts and contribute to public engagement activities. You will assist in the supervision of one or more postgraduate students whose projects are closely allied to the objectives of the grant. Experience with packages such as Fiji, Arivis and Imaris would be an advantage. You will work together with biologists and computational image analysts to study morphogenetic events underlying ear development, which involve movement, fusion and fission of epithelial sheets of cells.

This post is fixed-term for 12 months, with an immediate start date.

Job Description

Main Duties and Responsibilities
Conduct innovative research into the methods, development, implementation and deployment of software tools to analyse datasets generated by light-sheet microscopy for the Whitfield lab.
Liaise with members of the Frangi and Whitfield teams, and collaborating teams, to meet objectives of the BBSRC-funded project.
Planning and implementation of project goals and objectives at a short-term (3 month) level.
Analyse and record data to aid the design of future research and produce useful findings for other academics, funders, policy makers and practitioners.
Provide specialist training and supervision for postgraduate project students in the lab, and other members of the team, as required.
Read academic, journals and textbooks and attend conferences to keep abreast of new developments. Update and acquire new skills and knowledge in line with advances in the subject area, including technical expertise and experience.
Writing of manuscripts, reviews and reports.
 Presentation of research at scientific meetings, local and international, as required.
 Contribute to promotion of the research at various public engagement events.
Work within Health and Safety guidelines.
Any other duties, commensurate with the grade of the post.


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