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Research Associate in Cell and Developmental Biology

University of Sheffield

Sheffield, United Kingdom

A Wellcome Trust-funded Postdoctoral Research Associate position is available in the lab of Dr. Matt Towers that aims to understand how cells measure time during vertebrate limb development. We have recently shown that intrinsic timing mechanisms are involved in chick wing development. these intrinsic timers determine the duration of the important signalling
molecule sonic hedgehog (Chinnaiya et al, Nat Comms 2014) and specify the pattern of skeletal elements (Saiz-lopez et al, nat comms 2015; Saiz-lopez et al, development 2017). Using a combination of advanced grafting techniques in chick embryos and RNA sequencing we aim to understand if single limb bud cells have the ability to measure time in vivo and if their intrinsic developmental programmes can be re-set and re-executed.

The successful applicant will have a PhD in developmental biology (or equivalent experience) with experience of tissue grafting techniques and gene manipulation in chick embryos. Experience in RNA sequencing and bioinformatics is desirable.
The successful candidate will be expected to have excellent interpersonal and communication skills, be highly independent, and committed to research in a fast-moving and competitive field.

You can view the supporting documentation by clicking on the About the Job and About the University located near the top of your screen.

Job Description
Main Duties and Responsibilities
 Carry out research/experiments.
 Design, develop and refine experiments in order to obtain reliable data.
 Analyse and record data to aid the design of future research and produce useful findings for other academics, funders, policy makers and practitioners.
 Prepare papers for journals/presentations either in-house or at national/international conferences or seminars to disseminate research findings.
 Plan and prepare several months in advance for publications and conference presentations.
 Read and understand academic papers and journals, and attend seminars and conferences to keep abreast of developments in the field.
 Write supporting documents to contribute to and support the work of the Research Group, e.g. reports, interim reports and grant applications.
 If given a particular hypothesis to examine, plan for own contribution up to 3 months ahead, incorporating issues such as the availability of resources, deadlines, project milestones and overall research aims.
 Continuously monitor and check results. The unpredictability of research means that daily planning needs to accommodate new developments.
 Carry out administrative roles as required, e.g. ordering reagents.
 Contribute to the supervision of PhD students and other team members within the group.
 Contribute to the scientific wellbeing of the Research Group and Department.
 Any other duties, commensurate with the grade of the post.


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